Reactive Oxygen Species Signaling and Redox Homeostasis Regulated by 8-Nitro-cGMP

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[Reactive oxygen species signaling and redox homeostasis regulated by 8-nitro-cGMP].

An emerging aspect of redox signaling is the signaling pathway mediated by electrophilic byproducts, such as nitrated cyclic nucleotide (8-nitro-cGMP), generated via reactions of reactive oxygen species (ROS), NO, and their secondary products. We recently clarified that enzymatically-generated hydrosulfide derivatives regulate the metabolism and signaling of 8-nitro-cGMP. Although hydrogen sulf...

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ژورنال

عنوان ژورنال: YAKUGAKU ZASSHI

سال: 2014

ISSN: 0031-6903,1347-5231

DOI: 10.1248/yakushi.13-00251-3